Mike Verdon's Python Twitter Tools is less popular and findable than the Dewitt Clinton's python-twitter (I only found the former from an email on the latter's mailing list), but it's a beautiful library. 125 lines, most of which are comments. It implements the full API by implementing a single call class that handles everything (and that class is only a few lines). A good library to use if you're trying to access Twitter via Python, and a good source for learning and inspiration if you're writing a library / wrapper.